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Pancreatic islets
The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (i.e., hormone-producing) cells. Discovered in 1869 by German pathological anatomist Paul Langerhans. New studies show that the pancreatic islets constitute approximately 4.5% of the pancreas volume 〔 and receive 10-15% of its blood flow.〔(Functional Anatomy of the Endocrine Pancreas )〕 The islets of Langerhans are arranged in density routes throughout the healthy human pancreas.〔
==Structure==
There are about 3 million islets distributed in the form of density routes throughout the pancreas of a healthy adult human,〔 each of which measures an average of about 0.1 mm (109 µm) in diameter.〔:914 Each is separated from the surrounding pancreatic tissue by a thin fibrous connective tissue capsule which is continuous with the fibrous connective tissue that is interwoven throughout the rest of the pancreas.〔:914 The combined mass of the islets is 2 grams.〔 Islets of Langerhans can also form super structures called ''Islet clusters'' which are composed of small islets that surround large blood vessels.〔 The roundness of islets along the pancreas has also been quantified through the Index of Sphericity method.〔 Thus, the islets closest to the spherical form are mainly found in the pancreas tail whereas the islets farthest from the spherical form are found in the pancreas neck.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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